Surgical wound irrigations are used in the perioperative setting to decrease the microbial count as much as possible to aid in infection prevention. It is important for the perioperative team to be aware of the different types of antiseptics available and their sterility when applied in a sterile field or in wound irrigation. In the current era of antibiotic stewardship, with the prevalence of bacterial resistance to multiple antibiotic agents, there has been an interest in using perioperative antiseptics to reduce microbial contamination in the surgical site before closure and possibly reduce the need for antibiotic agents. This program is intended to better understand the proper implications of the different types of wound irrigations in relation to SSIs, cost, and efficiency.